No more impossible than any other precise quantum measurement. But that doesn’t have to be the goal post; indirectly making measurements, even on atoms worth of mass helps. Every time we change the setup, the mass, the temperature, the measurements, we can learn something new. Cast enough shadows from different angles and you’ll be able to model what’s casting the shadow. If you study condensed matter physics you’ll quickly learn there’s a lot to be learned and gained from indirect quantum measurements.